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MetWare Ltd
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BGI Genomics Co
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Metabologenomics Inc
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MetWare Ltd
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Suzhou PANOMIX Biomedical Tech Co Ltd
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Image Search Results
Journal: PLoS ONE
Article Title: A Metabologenomic approach reveals alterations in the gut microbiota of a mouse model of Alzheimer’s disease
doi: 10.1371/journal.pone.0273036
Figure Lengend Snippet: A) Workflow of the study. Fecal samples from WT and 3xTG mice at weaning, two and six months were collected and analyzed using metabolomic and metagenomic approaches. Metabolome and metagenome profiles were then analyzed and integrated to explore microbiome variations potentially associated with the progression of the disease. B) Circos plot of Spearman correlation between metabolite-phyla (left panel) and class-metabolites-phyla (right panel). A positive correlation is distinguished by red lines, while a negative correlation by green lines. C) Hierarchical heat maps with Spearman correlation between bacterial genera and metabolites (left panel), and with bacterial genera and metabolites-classes (right panel). The red color indicates a positive correlation, while the blue color indicates a negative correlation. The darker color indicates more statistical significance. Symbol * and ** indicates correlation coefficients smaller than 0.05 or 0.01, respectively.
Article Snippet: Finally, an integrated analysis combining both metagenomic (16S) and
Techniques: